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What (who) is pyruvate kinase - definition

CLASS OF ENZYMES

Pyruvate Kinase; EC 2.7.1.40; ATP:pyruvate 2-O-phosphotransferase

Pyruvate dehydrogenase kinase

Pyruvate dehydrogenase kinase (also pyruvate dehydrogenase complex kinase, PDC kinase, or PDK; ) is a kinase enzyme which acts to inactivate the enzyme pyruvate dehydrogenase by phosphorylating it using ATP.

https://en.wikipedia.org/wiki/Pyruvate_dehydrogenase_kinase

MAP kinase kinase kinase

Mitogen Activated Protein (MAP) kinase kinase kinase, MAPKKK (or MAP3K) is a serine/threonine-specific protein kinase which acts upon MAP kinase kinase. Subsequently, MAP kinase kinase activates MAP kinase.

https://en.wikipedia.org/wiki/MAP_kinase_kinase_kinase

Pyruvate dehydrogenase deficiency

CARBOHYDRATE METABOLIC DISORDER CHARACTERIZED BY THE BUILDUP OF LACTIC ACID IN THE BODY AND A VARIETY OF NEUROLOGICAL PROBLEMS AND CAUSED BY A DEFICIENCY OF ONE OF THE THREE ENZYMES IN THE PYRUVATE DEHYDROGENASE COMPLEX

Pyruvate dehydrogenase complex deficiency disease; Deficiency of pyruvate dehydrogenase

Pyruvate dehydrogenase deficiency (also known as pyruvate dehydrogenase complex deficiency or PDCD) is a rare neurodegenerative disorders associated with abnormal mitochondrial metabolism. PDCD is a genetic disease resulting from mutations in one of the components of the pyruvate dehydrogenase complex (PDC).

https://en.wikipedia.org/wiki/Pyruvate_dehydrogenase_deficiency

Wikipedia

Pyruvate kinase

Pyruvate kinase is the enzyme involved in the last step of glycolysis. It catalyzes the transfer of a phosphate group from phosphoenolpyruvate (PEP) to adenosine diphosphate (ADP), yielding one molecule of pyruvate and one molecule of ATP. Pyruvate kinase was inappropriately named (inconsistently with a conventional kinase) before it was recognized that it did not directly catalyze phosphorylation of pyruvate, which does not occur under physiological conditions. Pyruvate kinase is present in four distinct, tissue-specific isozymes in animals, each consisting of particular kinetic properties necessary to accommodate the variations in metabolic requirements of diverse tissues.

https://en.wikipedia.org/wiki/Pyruvate kinase